Investigation and Characterization of Alkaloidic Compounds from Apium graveolens and Estimation of their Antibacterial Activity

Apium graveolens is considered as one of traditional food plant spreading in various contries in the world and it has the excellent medical efficacy against diverse diseases. Three alkaloidic compounds were isolated, separated. and charaeterized by using gaschromatography-mas spectroscopy analysis. Also the mixture if there active chemical compounds was tested qualitatively using Dragendroff reagent Various concentrations are represented by 10, 25, 35, 50 and 65 mg ⁄ml were prepared from the alkaloidic mixture They recorded different inhibition diameters values equal to 3 , 13 , 21 , 23 and 25 mm against growth of Staphylococcus bacteria. while the same concentrations showed inhibition values are represented by 11 , 21 , 23 , 25and 27 mm towards Bacillus subtillus bacteria. It was noticed that five alkaloidic compounds mixture was more effective against Bacillus subtillus than Staphylococcus aureus bacteria. As a result, the active alkaloids can be used as potent natural therapy for diverse diseases caused by these pathogenic bacteria .