Synthesis and Characterization of 5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one: A Possible Prosthetic Group for Indirect Radiolabeling of Carbonyl-Containing Compounds

5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one was prepared in a two-step process. A new β-Carboethoxy hydrazine was prepared first, and then, a new 1,3,4-oxadiazole-2-one, was prepared, both new compounds were identified by MP, IR, 1H NMR, and elemental analysis. The new 1,3,4-oxadiazole-2-one is a possible prosthetic group when iodinated, it could be approved as a method for indirect radiolabeling of carbonyl-containing compounds.