An Attempt to Understand Entropy Trends in a Model Independent Protein Aggregation Process

The dynamics of protein aggregation is of extreme importance due to its directconnection with neuro-degenerative diseases such as Parkinson’s, Alzhiemer’sand Motor Neuron Disease, just to name a few. These diseases are very com-plex in nature and require a deep understanding of the interactions betweenprotein-protein structures and the dynamics of the aggregation process. Thecomplexity of protein aggregation increases as the aggregate progresses. Thisprogression and the complexity of the molecules increases at various levels.There have been numerous theoretical and experimental studies on protein ag-gregation and we have a good enough understanding, but there is still a big gapin understanding the dynamics of the process of protein aggregation. We areshowing the protein aggregation process from the point of view of an entropyincrease trend.