Supplementary Fig. 5 from Spatial profiling of circular RNAs in cancer reveals high expression in muscle and stromal cells

Analysis of Ki67 staining on colon adenocarcinoma and adjacent normal tissue sections. Representative Ki67 staining from tumor (left) and adjacent normal (right) tissues from the five patients’ samples subjected to the analysis. Positive staining is visible as brown color. In the tumor tissues, Ki67 is clearly present in the cancer cells and in some cells in the tumor stroma. In the normal tissue sections, the positive staining is found at the bottom of the crypts in the epithelium whereas no staining is detected in the mucosa and muscle sub-compartments.