Tissue markers specificity. Normalized NanoString counts from specific tissue markers used for sub-compartment purity assessment after laser capture microdissection. KRT8, CDX2 and SATB2 are epithelial markers. VIM is an activated stromal marker and ACTA2 and DES are muscle cell markers. Parametric t-tests were performed to compute the p-values using the values from the cancer cells as reference. The box represents the interquartile range (Q1 and Q3), the median is marked with a horizontal line, and whiskers represent minimum and maximum values.
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García‐Rodríguez et al. (2024) studied this question.
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