Metastasis of the bladder is an exceptionally rare occurrence in primary breast cancer. We report the case of a 68-year-old woman with a history of lobular breast carcinoma who developed metastatic bladder involvement ten years after her initial treatment. Cystoscopy and biopsy confirmed submucosal infiltration by carcinoma with an immunohistochemical profile consistent with lobular breast carcinoma, featuring estrogen receptor-positive and human epidermal growth factor receptor 2 (HER-2) negative. The therapeutic decision recommended was to start first-line treatment with Fulvestrant plus Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors.
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Salhi et al. (2024) studied this question.
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