Introduction: Metallo-beta-lactamase producing Pseudomonas aeruginosa is an important emerging nosocomial pathogen, due to its ability to acquired drug resistance. Aim & objectives: The aim of this study was to detect MBL encoding genes by genotypic method among clinical isolates of Pseudomonas aeruginosa. Material & Method: A total of 50 non-repetitive isolates of P. aeruginosa recovered from various clinical samples were included in this study. All these isolates were screened for MBL production by RT-PCR irrespective of imipenem sensitivity and the presence of blaVIM, blaIMP & blaNDM was determined. Results: Out of 50 isolates of P. aeruginosa, MBL were detected in 32 (64%) isolates by PCR. blaVIM gene was detected in 21 isolates, followed by blaNDM in 11 isolates and blaIMP in 5 isolates. Conclusion: The prevalence of MBLs among Pseudomonas aeruginosa has been increasing. This study confirms a high rate of MBL production & dissemination of blaVIM gene among Pseudomonas aeruginosa.
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Upadhyay et al. (2024) studied this question.
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