Cs2CO3‐Mediated Tandem Dimerizative (3+3) Cyclocondensation of 1,3‐Acetonedicarboxylates. One‐pot Synthesis of 2,4,6‐Trialkoxy and Triaryloxybenzoates

In this study, Cs2CO3‐mediated one‐pot tandem dimerization/(3+3) cyclocondensation of 1,3‐acetonedicarboxylates followed by substitution of alkyl or aryl halides was developed to construct functionalized 2,4,6‐trialkoxy and triaryloxybenzoates. In the effective reaction, the core benzene system was formed in single‐step process under open‐vessel conditions. A plausible mechanism for this reaction is proposed and discussed herein.