⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

September 3, 2024Organic Letters

Pyridine-Catalyzed Chemoselective Four-Component Cascade Reaction of Aromatic Aldehydes, Malononitrile/Cyanoacetates, MBH Carbonates, and Alcohols

Boning Li Xianfei Hu Hui Yao Yi Li Dan Xu Nianyu Huang Nengzhong Wang

View Full Paper

Ask AI

Bookmark

Share

Abstract

An efficient pyridine-catalyzed chemoselective four-component cascade reaction of aromatic aldehydes, malononitrile/cyanoacetates, Morita-Baylis-Hillman (MBH) carbonates, and alcohols has been established. This one-pot reaction progressed in an unusual reaction with solvent participation via a Knoevenagel condensation/oxa-Michael addition/S

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Li et al. (2024) studied this question.

synapsesocial.com/papers/68e597d2b6db64358753222e https://doi.org/10.1021/acs.orglett.4c02612

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Pd-Catalyzed Four-Component Cascade Cyclization of Alkynols, Aryl Iodides, CO, and Amines2025 · 2 citations
2Oxa-Michael Cascade [4+2] Annulation of Pyrazoledione-derived Morita–Baylis–Hillman (Pyro-MBH) Alcohols with Arylidene Pyarazolones: One pot Access to Dispiropyrazolone fused Tetrahydropyran2025
3Iron-catalyzed One-Pot Four-Component Synthesis of Dihydropyridinones from Benzyl Alcohols and Ketones2025
4Multicomponent Assembling of Aldehydes, <i>N</i>,<i>N</i>‐Dimethylbarbituric Acid, Malononitrile, and Morpholine Into Unsymmetrical Ionic Scaffold and Its Efficient Cyclization2024 · 1 citations
5Synthesis of Substituted N-Heterocycles via Cascade, Michael Addition, Double Cyclization and Air Oxidation ReactionOriginal Research · 2025 · 1 citations