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September 1, 2024Nucleic Acids ResearchOpen Access

Modulation of dynamic DNA G-quadruplex structures in the hTERT promoter region by ligands

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Authors

DKDeepak KarnaLLLin LiangGSGrinsun Sharma

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Karna et al. (2024) studied this question.

synapsesocial.com/papers/68e59c4cb6db6435875367e6https://doi.org/10.1093/nar/gkae754
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Recognition and Imaging of Human Telomeric G-Quadruplex DNA in Live Cells: A Systematic Advancement of Thiazole Orange Scaffold To Enhance Binding Specificity and Inhibition of Gene Expression2021 · 30 citations
  2. 2Formation of a Unique End-to-End Stacked Pair of G-Quadruplexes in the hTERT Core Promoter with Implications for Inhibition of Telomerase by G-Quadruplex-Interactive Ligands2009 · 292 citations
  3. 3G‐Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy2017 · 571 citations
  4. 4Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues2021 · 93 citations
  5. 5The hTERT core promoter forms three parallel G-quadruplexes2020 · 104 citations