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Shows elevated serum LOXL2 acts as an independent biomarker in coronary artery disease, highlighting its connection to arterial stiffness and inflammation.
Arterial stiffness is associated with accelerated progression of atherosclerosis and plaque rupture. Lysyl oxidase-like 2 (LOXL2) plays a vital role in inflammatory responses, matrix deposition and arterial stiffness. This study assessed the correlation between the serum LOXL2 concentration and disease severity, inflammation, and endothelial dysfunction of coronary artery disease (CAD).
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Zhongsheng Zhu (2024) studied this question.
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