Detection of Typical and Blast Cells in Acute and Chronic Leukaemia Using the Manual Method and Hematology Analyzer BC-720

Introduction: Diagnosing Leukaemia requires precise identification of atypical whiteblood cells. This research aims to compare the effectiveness of the BC-720 analyzerand manual microscopy in identifying blast and typical cells in both acute and chronicLeukaemia. Manual microscopy and the BC-720 analyzer were used to investigatedifferential white blood cell counts from 68 Leukaemia patients and 18 controls.Sensitivity and error rates for detecting abnormal cells were evaluated. The manualapproach had a recognition loss of 12%, but successfully identified 47.1% of cases. TheBC-720 identified 52.9% of cases, with higher detection rates in chronic patients(41.2%) and control cases (5.9%). In acute cases, the detection loss was 8.0% lower.Both methods showed advantages and limitations. The BC-720 demonstrated higherdetection rates for abnormal cells, particularly in acute Leukaemia, and lowerrecognition losses compared to manual microscopy. It can aid in more accurateLeukaemia classification and management.