On the pathogenesis and treatment of infectious-toxic (endotoxic) shock

The article is devoted to the issues of etiology, pathogenesis, classification, basic approaches to the diagnosis and treatment of infectious-toxic shock. Despite progress in studying the pathophysiology of sepsis and the development of new antibacterial drugs, mortality from endotoxic shock remains high. In recent years, antishock vaccines have been actively developed, but they have not yet received widespread use in clinical practice. The introduction of these drugs in the future may contribute to the survival of patients with various pathologies, as well as those in the “shock” risk group (military, emergency services personnel, etc.).