A simple spectrophotometric technique has been developed and validated for determination of betamethasone 17-valerate in pharmaceutical formulations. The method is based on cream dissolution in absolute ethanol and assaying spectrophotometrically at 240nm. The amount of betamethasone 17-valerate in cream was determined as 101.6 ± 0.0037 % w/w. The method validation demonstrated linearity for concentration range of 0.006mg/ml to 0.0014mg/ml (R2=0.9995). The method is simple and accurate and has successfully been employed in the analysis of some of Tripharm pharmaceutical formulations.
No takes yet. Share an insight, caveat, or question.
Beleme et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: