August 27, 2024

Exploring the potential mechanisms of Galla chinensis in anti-breast cancer using HS-SPME-GC-MS and bioinformatics

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Authors

BHBin HuangFujian University of Traditional Chinese Medicine HJHeng JiangChengdu Second People's Hospital YTYanhua TangNanchang University

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Implication

Chromatographic and bioinformatics profiling reveals anti-breast cancer targets of Galla chinensis volatiles in human tissues, highlighting novel metabolic pathways.

Key Points

Volatile components from Galla chinensis may suppress breast cancer by targeting MAOA and MAOB hub genes, thereby disrupting critical drug metabolism pathways.
Analysis identified 10 candidate compounds from 28 volatile constituents that modulate MAOA and MAOB hub genes to disrupt breast cancer pathogenesis.
Bioinformatics methods and HS-SPME-GC-MS chemical profiling mapped active volatile constituents, highlighting potential therapeutic avenues for breast cancer research.

Cite This Study

Huang et al. (2024) studied this question.

synapsesocial.com/papers/68e5ac88b6db64358754605b https://doi.org/10.1117/12.3044112

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Implication

Chromatographic and bioinformatics profiling reveals anti-breast cancer targets of Galla chinensis volatiles in human tissues, highlighting novel metabolic pathways.

Exploring the potential mechanisms of Galla chinensis in anti-breast cancer using HS-SPME-GC-MS and bioinformatics

Discussion

Member takes

Implication

Key Points

Cite This Study

Exploring the potential mechanisms of Galla chinensis in anti-breast cancer using HS-SPME-GC-MS and bioinformatics

Discussion

Member takes

Implication

Key Points

Cite This Study

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