Essential oils with anti-breast cancer activities from Aralia chinensis L. (roots, stems, and leaves) via gas chromatography–mass spectrometry analyses and molecular docking

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In vitro analysis demonstrates essential oils from Aralia chinensis inhibit MCF-7 breast-cancer cells, indicating therapeutic potential.

Essential oils from Aralia chinensis rhizomes, stems, and leaves inhibited the viability of MCF-7 breast-cancer cells by 77%, 64%, and 62%.
Gas chromatography-mass spectrometry identified 35, 35, and 24 volatile constituents across plant roots, stems, and leaves, respectively.
Network pharmacology identified AKT1, SRC, and EGFR as primary targets, supporting antitumour activity; in vitro cell model requires validation.

Xue et al. (2024) studied this question.

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