Background Spindle cell squamous cell carcinoma (SpSCC) is a rare subtype of squamous cell carcinoma (SCC) showing an unfavorable prognosis. Histologically, SpSCC shows biphasic proliferation of spindle cells and nests of SCC. Case presentation An 85‐year‐old Japanese man with a medical history of oral SCC three years ago had SpSCC of the right maxillary sinus. The tumor showed aggressive proliferation of spindle cells with nests of conventional SCC. Subsequent lymph node metastases revealed findings of conventional SCC. Conclusion This case report contributes to the accumulation of a rare subtype of SCC and multiple cancers of the head and neck region.
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Shima et al. (2024) studied this question.
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