Spindle Cell Carcinoma of Mandible – A Case Report

Spindle cell squamous carcinoma (SpCC) is an exceedingly rare variant of squamous cell carcinoma (SCC) with unique clinicopathological characteristics. SpCC of the head and neck is a rare, biphasic neoplasm rst described by Virchow (1865). It is composed of SCC, either in situ and/or in invasive form, and a malignant spindle cell component with a mesenchymal appearance, but of epithelial origin. It compromises less than 1% of all oral cavity tumours, and it has a site predilection for the alveolar mucosa, tongue, buccal mucosa, and lower lip. SpCC exhibits similar demographics to the conventional squamous cell carcinoma, with a higher prevalence in males but primarily in the 5th and 6th decades of life. Here, we present a case of SpCC of the posterior part of mandible in the left side in a 50-year-old male which had a rapid growth.