August 24, 2024EsophagusOpen Access

Validation of the cutoff values for the number of metastatic lymph nodes for esophageal cancer staging: a multi-institutional analysis of 655 patients in Japan

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KTKoji TanakaOsaka Gakuin University TFTakeo FujitaNational Cancer Center Hospital East YNYasuaki NakajimaEdogawa Hospital

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Implication

Multi-institutional analysis reveals conventional pathologic lymph node cutoffs predict survival in esophageal cancer, indicating staging validity following neoadjuvant therapy.

Key Points

Pathologic nodal categories reliably preserve prognostic stratification in esophageal cancer, whereas clinical staging fails to predict survival after neoadjuvant therapy.
Significant differences with p < 0.0001 separated survival across pathologic groups, whereas clinical metastatic lymph nodes stages showed no distinction with p = 0.5675.
Multi-institutional analysis of esophagectomy cohorts using the Kaplan–Meier method confirms tumor node metastasis staging cutoffs, supporting standard clinical practice.

Cite This Study

Tanaka et al. (2024) studied this question.

synapsesocial.com/papers/68e5b13eb6db64358754a90f https://doi.org/10.1007/s10388-024-01084-6

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Implication

Multi-institutional analysis reveals conventional pathologic lymph node cutoffs predict survival in esophageal cancer, indicating staging validity following neoadjuvant therapy.

Validation of the cutoff values for the number of metastatic lymph nodes for esophageal cancer staging: a multi-institutional analysis of 655 patients in Japan

Discussion

Member takes

Implication

Key Points

Cite This Study

Validation of the cutoff values for the number of metastatic lymph nodes for esophageal cancer staging: a multi-institutional analysis of 655 patients in Japan

Discussion

Member takes

Implication

Key Points

Cite This Study

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