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August 22, 2024International Journal of Molecular SciencesOpen Access

Nuclear Localization of Human SOD1 in Motor Neurons in Mouse Model and Patient Amyotrophic Lateral Sclerosis: Possible Links to Cholinergic Phenotype, NADPH Oxidase, Oxidative Stress, and DNA Damage

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Authors

LMLee J. MartinJohns Hopkins UniversitySKShannon J. KohJohns Hopkins UniversityAPAntionette PriceJohns Hopkins University

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Martin et al. (2024) studied this question.

synapsesocial.com/papers/68e5b4dfb6db64358754d825https://doi.org/10.3390/ijms25169106
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  5. 5Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic2022 · 32 citations