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Reveals mid-regional pro-adrenomedullin as a marker of vascular integrity and congestion in acute heart failure, suggesting potential utility in guiding targeted decongestive therapies.
Congestion is a major determinant of outcomes in acute heart failure. Its assessment is complex, making sufficient decongestive therapy a challenge. Residual congestion is frequent at discharge, increasing the risk of re-hospitalization and death. Mid-regional pro-adrenomedullin mirrors vascular integrity and may therefore be an objective marker to quantify congestion and to guide decongestive therapies in patients with acute heart failure.
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Beer et al. (2024) studied this question.
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