A palladium‐catalyzed cascade cyclization and alkynylation of 2‐alkynylphenols with bromoalkynes to the synthesis of 3‐alkynylbenzofuran scaffolds has been developed. A variety of 3‐alkynylbenzofuran derivatives were prepared in good yields under mild conditions. Notably, this protocol was applied to the late‐stage modification of bioactive molecule.
No takes yet. Share an insight, caveat, or question.
Feng et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: