Surgical Management of Parry-Romberg Syndrome: An in-Depth Review of Techniques and Outcomes

Parry-Romberg Syndrome (PRS), also known as progressive hemifacial atrophy, is a rare, poorly understood disorder characterized by the progressive atrophy of the skin, subcutaneous tissue, and sometimes bone on one side of the face. The etiopathogenesis of PRS remains elusive, and its clinical presentation can vary widely, complicating diagnosis and treatment. This review aims to provide a comprehensive overview of the current surgical management strategies for PRS, focusing on reconstructive techniques, postoperative outcomes, and patient quality of life. Through an extensive literature review and analysis of case studies, we highlight the efficacy of various surgical interventions, such as autologous fat grafting, dermal fat grafts, and microsurgical free tissue transfer, in restoring facial symmetry and function. We also discuss the challenges and considerations in timing and planning surgical interventions, as well as the role of multidisciplinary approaches in optimizing patient care.