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Through T1, T2, and fat fraction mapping, MRI is a formidable tool for the comprehensive assessment of liver health, but has been held back by slow, 2D, single-parameter mapping sequences. We propose a novel respiratory-motion-corrected framework to acquire all three of these maps from a single 6.5-minute scan, on the latest generation of 0.55T scanner. The resulting maps are 3D, with 3 mm isotropic resolution, and co-registered, making them suitable for multiparametric assessment of tissue health. Liver joint T1, T2, and fat fraction maps are in good agreement with reference values and first in-vivo scans provide promising image quality.
Tripp et al. (Wed,) studied this question.