Remote Pneumatic Dose Administration for 129Xe MRI: Effects on Lung Inflation and Patient Experience

Hyperpolarized 129Xe MRI requires repeatable lung inflation volumes to ensure consistent and accurate data. Current dose administration techniques require specialized study personnel to not only properly coach the subject through the inhalation maneuver, but also to directly administer the 129Xe dose, often while leaning deep into the MRI bore. Since lung inflation directly affects imaging data, it is important to maximize the consistency of inflation volumes across imaging sessions. We propose a novel 129Xe gas administration device intended to mitigate lung inflation differences as well as allow for remote administration of doses from outside the bore.