Evaluation of the clinical value of Synthetic MRI in the prostate cancer diagnosis: a comparison of quantitative relaxation with conventional MRI

This study aimed to investigate the feasibility of synthetic MRI in distinguishing PCa from benign hyperplasia, and quantitative relaxation was compared with conventional MRI to evaluate the precision of obtained values with synthetic MRI. 38 patients (54 lesions) with cancer and/or hyperplasia were recruited. Quantitative MRI sequences, including T1, T2 mapping and MAGIC, were used. Significantly different T1 and T2 values were shown between cancer and noncancerous tissue, located in peripheral and center zones, as well as between cancer and glandular hyperplasia and stromal hyperplasia. These findings suggest synthetic-MRI may be effective in differentiating PCa from benign hyperplasia.