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Revealing the association of amyloid PET and metabolic MRI measurements would be useful for future studies or clinical situations that evaluate Alzheimer's disease (AD). We investigated the relationship between imaging measurements and clinical information in 29 AD patients and age- and sex-matched normal controls (NCs) using OASIS-3 dataset. A significant positive correlation was found between brain temperature and index of diffusivity along the perivascular space (ALPS index) among all subjects and NCs, while a significant negative correlation was found between age and ALPS index among all subjects, AD patients, and NCs.
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Matsushita et al. (2024) studied this question.
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