Differential diagnosis for hypertrophic cardiomyopathy and hypertensive heart disease by layer-specific CMR strain analysis

This study evaluated the left ventricle (LV) and right ventricle (RV) layer-specific (endocardium=Endo, epicardium=Epi, myocardium=Myo) strain of hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD). We also evaluated the ability of left atrium (LA) to differentiate HCM and HHD. The strain and strain rate were calculated from CMR. The difference of LV between HCM and HHD was endocardium. The difference of RV was free wall epicardium. The difference of LA was LA strain at conduit phase (LAS-cd). Combining the LV global circumferential strain rate of endocardium (GCSR-Endo) and LASR-cd can better differentiate HCM and HHD.