Evaluation of multi-echo ICA denoising for an olfactory task experiment.

To remove noises from fMRI signals, ME-ICA was proposed. However, it is still unclear whether the denoising method shows good performance for an olfactory task experiment. Here, we compared the GLM and MVPA results between conventional denoising method and ME-ICA. In the 2nd level GLM, ME-ICA showed larger activation than conventional one, which is in line with the previous studies for visual or auditory experiments. On the other hand, ME-ICA did not show better MVPA performance. In conclusion, ME-ICA was a good denoising method for an olfactory experiment, but the benefit was small for MVPA.