Cine T2 mapping reveals cardiac cycle-dependent T2 variability in cardiomyopathy

We have successfully developed cardiac cine imaging to project T2 values using T2prep-based T2 mapping with dynamic multiple trigger-delay framework. We have demonstrated that diastolic T2 values on cine T2 mapping are temporarily prolonged in patients with non-ischemic cardiomyopathy and impaired left ventricular function. Cine T2 mapping is a new noninvasive in vivo imaging technique for myocardial edema that provides an effective means of elucidating the pathogenesis of cardiomyopathy.