Key result
T1 and T2 mapping in cardiac magnetic resonance imaging provides quantitative evaluation of myocardial tissue properties, improving the diagnosis and risk stratification of nonischemic cardiomyopathies.
Why the study?
Does T1 and T2 mapping in cardiac MRI improve diagnostic accuracy compared to conventional MRI in patients with nonischemic cardiomyopathy?
Does T1 and T2 mapping in cardiac MRI improve diagnostic accuracy compared to conventional MRI in patients with nonischemic cardiomyopathy?
T1 and T2 mapping in cardiac MRI enhances diagnostic accuracy and risk stratification for nonischemic cardiomyopathy compared to conventional MRI.
May aid CMR-based diagnosis in nonischemic cardiomyopathies; leaves open standardization and prospective outcome validation.
Cardiac magnetic resonance imaging is instrumental in diagnosing various cardiovascular diseases. Recently introduced T1 mapping and T2 mapping sequences have enabled quantification of the T1 and T2 relaxation times of the myocardium and associated cardiovascular structures, which are intrinsic properties of tissues. These sequences have been increasingly used to diagnose cardiomyopathy based on changes in the T1 and T2 relaxation times and to objectively quantify the severity of cardiomyopathy. As reference values in T1 and T2 mapping sequences are influenced by specific techniques or magnetic field strength, they are limitations. However, parametric imaging with native T1, T2, and extracellular volume fraction (%) values yields a higher diagnostic accuracy than conventional MRI and is useful for diagnosis, treatment, and risk stratification of cardiomyopathy.
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Fundikira et al. (2018) conducted a review in Nonischemic Cardiomyopathy. T1 and T2 mapping cardiac MRI vs. Conventional MRI (LGE) was evaluated. T1 and T2 mapping in cardiac magnetic resonance imaging provides quantitative evaluation of myocardial tissue properties, improving the diagnosis and risk stratification of nonischemic cardiomyopathies.
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