In this study, we investigated diurnal changes in cerebral hemodynamics from 4D-Flow in a large population of cognitively healthy older adults and in a younger group of healthy volunteers. To separate physiological and technical variability of 4D-Flow measures, volunteers were scanned at 7am, 4pm, and 10pm on the same day three times for each timepoint. Data supports strong cerebral blood flow fluctuations of physiological origin that are much higher than the technical variability.
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Rivera‐Rivera et al. (2024) studied this question.
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