Reliability and reproducibility of whole-brain quantitative MR relaxometry using different-channel-number coils

Brain MAGiC imaging became widely applied in multi-center cooperation and in an individual longitudinal follow-up; however, acquisition with a backup coil at an emergency situation (i.e., a sudden coil breakdown) or a coil with different numbers of channels has not been explored on a 1.5T scanner yet. In contrast to small variation of PD values in the whole brain, T2 values varies relatively dramatically especially in cerebellum and showed statistically different between scans using different coils. It is worth noting that existence of inter-coil relaxometry difference should be careful for diagnosis.