Colorectal cancer’s pathological prognostic factors directly affect the patient's prognosis. Golden-angle RAdial Sparse Parallel (GRASP) imaging was invented to calculate the accurate perfusion parameters including influx forward volume transfer constant (Ktrans), rate constant (Kep), and plasma volume fraction (Ve). We found GRASP parameters showed significant differences in many prognostic factors, including histology type, extramural venous invasion (EMVI), lymphovascular invasion (LVI), tumor deposit (TD) and lymph node metastasis (LNM), and were independent factors for histology type, LNM, LVI and EMVI. GRASP parameters were strongly associated with preoperative prognostic factors in rectal cancer, providing useful information for treatment and follow-up protocol.
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Zhou et al. (2024) studied this question.
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