We combined multiple rs-fMRI indices to investigate the abnormal functional changes among T2DM patients. 52 T2DM patients and matched control participants were enrolled in this study. The functional abnormalities primarily involved motor and sensory function areas. More brain regions were revealed by the combination strategy than any single method and the indices of rs-fMRI showed significantly concordant alterations in most abnormal brain regions. Correlations of between clinical parameters and rs-fMRI indices were found. The current study demonstrated an enriched picture showing the brain functional alterations reflected by the combination of multiple indices in T2DM patients.
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Zhang et al. (2024) studied this question.
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