APT-related metric maps were applied to differentiate subtypes and genotypes of adult-type diffuse gliomas following the latest 2021 WHO guidelines. One hundred and twenty-nine patients were imaged on a 3T scanner. Regions of interest were obtained with an automatic segmentation algorithm on conventional anatomical images, which were then resampled and matched with the CEST images. The mean CEST metric values were calculated in the automatically-defined regions of interest, and the receiver operating characteristic analysis was implemented, achieving generally successful performance in identifying the IDH status and part of the subtypes.
No takes yet. Share an insight, caveat, or question.
Jiang et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: