Spectrally Selective On-Resonance Inversion Recovery at 7T for Multiple Component T1 Mapping

Two sets of images were acquired on four healthy subjects using separate on-resonance selective and broadband inversion recovery (IR) sequences at nine different inversion times. These images were fit to a bi-exponential T1 fitting model aiming to separate out specific long and short components. The selective IR data showed a substantial increase in white matter contrast compared to the broadband data with an average T1 of approximately 300ms. This agrees with reported literature values of the T1 of myelin and suggest it may be a potential driver of this selective short T1 component contrast.