Keyword: Neuroimaging, type 2 diabetes mellitus, VBM, resting-state fMRI, Cognition The main purpose of this study was to evaluate the structural brain alterations and related functional abnormity of type 2 diabetes(T2DM), and its correlation with cognitive scale. Changes in brain volume were assessed using voxel-based morphology (VBM), while VBM Results were used to build ROI to analyse related functional connectivity (FC) changes in brain function. The result indicated that decreased gray matter volume and decreased functional connectivity may represent the neurobiological mechanism underlying cognitive dysfunction in patients with T2DM.
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Zhang et al. (2024) studied this question.
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