Dynamic contrast-enhanced (DCE) MRI incorporates arterial input function and pharmacokinetic models to assess tissue perfusion, vasculature, capillary permeability, and interstitial space volume. It can be used to assess tumor vascularization, which can help determine tumor aggressiveness and the degree of angiogenesis and monitor therapy. However, the relationship between pathological characteristics of rectal cancer and the quantitative analysis of DCE remains unclear.
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Yuan et al. (2024) studied this question.
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