Dynamic glucose-enhanced imaging of the liver using breath-hold black blood quantitative T1rho MRI

Non-alcoholic fatty liver disease (NAFLD) is often associated with abnormal metabolic syndrome. In this study, we investigated dynamic glucose enhanced imaging of the liver using T1rho MRI after glucose ingestion. We hypothesize this approach can be used to assess metabolic activities in the liver. Sixteen young volunteers and four patients with NAFLD were recruited in this study. The preliminary results suggest that the proposed approach has the potential to detect metabolic variations between normal subjects and subjects with fatty liver.