Reproducibility of diffusion tensor image analysis along the perivascular space (DTI-ALPS) on variable diffusion times

Diffusion tensor imaging (DTI) allows noninvasively to investigate the function of glymphatic system with ALPS index by utilizing the behavior of water molecules along the perivascular space. The effects of diffusion time with fixed TE for the evaluation of glymphatic system using diffusion tensor imaging have not been investigated. Here, we evaluated the effects of DTI with different diffusion time to ALPS index in the glymphatic system.