PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 5, 2026Radiology42 citations

Comparing Glymphatic Function Measures: Diffusion Tensor Image Analysis Along Perivascular Spaces (DTI-ALPS) versus Intrathecal Contrast-Enhanced MRI

View Full Paper
IMIngrid MossigeLVLars Magnus ValnesTST. Storås

Key Points

  • The research aims to assess the effectiveness of DTI-ALPS in measuring glymphatic function compared to intrathecal contrast-enhanced MRI.
  • Compared the DTI-ALPS method to contrast-enhanced MRI
  • Analyzed brain glymphatic function markers
  • Used imaging techniques to assess perivascular spaces
  • DTI-ALPS did not accurately reflect glymphatic function
  • Contrast-enhanced MRI showed more reliable biomarkers
  • Findings suggest limitations of noninvasive measures for assessing glymphatic function

Abstract

The analysis along the perivascular space index, a proposed noninvasive glymphatic function marker obtained at diffusion-tensor image analysis along perivascular spaces, did not reflect brain glymphatic function as ascertained with intrathecal contrast-enhanced MRI.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Mossige et al. (2026) studied this question.

synapsesocial.com/papers/69843553f1d9ada3c1fb4023https://doi.org/10.1148/radiol.252070
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diffusion Tensor Image Analysis ALong the Perivascular Space (DTI-ALPS): Revisiting the Meaning and Significance of the Method2024 · 361 citations
  2. 2Advances in functional and structural MR image analysis and implementation as FSL2004 · 14,328 citations
  3. 3Evaluation of Diffusion Tensor Imaging Analysis Along the Perivascular Space as a Marker of the Glymphatic System2024 · 73 citations
  4. 4Diffusion tensor imaging along the perivascular space: the bias from crossing fibres2024 · 49 citations
  5. 5Glymphatic clearance function in patients with cerebral small vessel disease2021 · 486 citations