New biomaterial for 3D cell modeling and NMR analysis: low signal interference and high diffusion for robust metabolic studies in-vitro

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Due to its non-invasive nature, NMR has become a pillar as a diagnostic technique, as well as a support for biochemical assays and disease tracking both in vivo and in-vitro. However, due to its magnetic susceptibility, some of the materials used for tissue engineering and 3D cell modeling are incompatible with the technique, interfering with data acquisition and reducing its applications in-vitro. We developed a cryogel that could help bridge this gap between NMR and tissue engineering.