The value of amide proton transfer and glucose-chemical exchange saturation transfer in predicting tumor grading and staging in cervical cancer

What are the values of three-dimensional amide proton transfer (APT) imaging and glucose-chemical exchange saturation transfer (glucoCEST) in WHO grading and staging of cervical cancer? We performed 3D-APT, 3D-glucoCEST, and DWI scans in 19 cervical cancer cases. APT signal intensity(SI), and GlucoCEST SI could distinguish high-grade from low-grade; GlucoCEST SI can differentiate early (<IIB) from advanced (≥IIB) cervical cancer. Both APT and glucoCEST can be used for the preliminary evaluation of cervical cancer, but glucose CEST has advantages in the evaluation of cervical cancer grading and staging.