This study aimed to develop multiparametric physiologic MRI-based spatial habitat analysis and to validate the association between the habitats and the molecular subtypes. The distinct tumor habitats were identified using multiple MRI-parameter maps, then applied to calculate the volume fraction and fractal dimension (FD) and to investigate their diagnosis value. The combination of FD and volume fraction improves the discriminatory ability for TNBC from non-TNBC with an AUC to 0.951 from 0.853.
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Xu et al. (2024) studied this question.
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