Fast Submillimeter QSM for Simultaneous QSM/MRSI of the Brain at 7T

The feasibility of simultaneous QSM and MRSI has been recently demonstrated using SPICE. But the resolution of QSM obtained by SPICE at 7T is limited to only 3 mm due to bandwidth requirements. To overcome the resolution limitation, this work proposes a fast acquisition sequence for high-resolution encoding, and a model-based method to reconstruct from sparse sampling. As a result, submillimeter QSM can be achieved within only 1 minute, which enables simultaneous QSM (at 0.8 mm) and MRSI (at 3.0 mm) in an 8-minute scan at 7T.