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Multicenter study reveals consistent ADC values but variable T1 and T2 parameters in cervical cancer patients, highlighting the need to account for institutional variations.
The reproducibility of quantitative MRI parameters in a multicenter setting is not trivial. In this study we evaluated the in-vivo multicenter consistency of quantitative MRI parameters in cervical cancer patients. DWI, T2 mapping and T1 mapping were available from 66 patients from 3 institutes. ADC values were measured consistently across institutes despite differences in acquisition protocols. For T2 and T1 values differences between institutes were observed, which need to be accounted in future evaluation of the quantitative MRI parameters in relation to treatment outcome.
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Houdt et al. (2024) studied this question.
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