Pd‐Catalyzed Allylic Substitution using Nucleophilic Amines: Access to Functionalized Mono‐ and Bis‐N‐Allyl Synthons

We here report a catalytic strategy to enable the decarboxylative allylic amination of vinyl cyclic carbonates using various aliphatic and nucleophilic amines. The use of a protic medium and chelating diphosphine ligands are the main drivers towards chemoselective allylic amine formation, thereby minimizing undesired ligand‐driven complex speciation and aminolysis of the involved substrate. This improved approach amplifies the repertoire of allylic amine synthons that can be prepared from a variety of substrate combinations.