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August 8, 2024Open Access

SKAP binding to microtubules reduces friction at the kinetochore-microtubule interface and increases attachment stability under force

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Authors

MRMiquel Rosas-SalvansCRCaleb J. RuxMDMoumita Das

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Cite This Study

Rosas-Salvans et al. (2024) studied this question.

synapsesocial.com/papers/68e5cfffb6db643587566598https://doi.org/10.1101/2024.08.08.607154
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The spindle protein CKAP2 regulates microtubule dynamics and ensures faithful chromosome segregation2024 · 6 citations
  2. 2Microtubule end stabilisation by cooperative oligomers of Ska and Ndc80 complexes2026
  3. 3BPS2026 – Mammalian metaphase kinetochores are deformable, elastic materials dependent on condensin for structural robustness and functional integrity2026
  4. 4BPS2026 – Mechanical forces on microtubule lattice affect kinesin1 binding in an isoform dependent manner2026
  5. 5An Aurora Kinase A/TPX2 complex phosphorylates CKAP2 to control mitotic spindle growth2025