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August 5, 2024Journal of Vascular Surgery Venous and Lymphatic DisordersOpen Access

Perioperative and intermediate outcomes of patients with pulmonary embolism undergoing catheter-directed thrombolysis vs percutaneous mechanical thrombectomy

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Authors

JTJunji TsukagoshiThe University of Texas Medical Branch at GalvestonBWB WickJohn Sealy HospitalAKAbbas KarimJohn Sealy Hospital

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Implication

Retrospective cohort study reveals reduced bleeding events and lower heart failure rates with mechanical thrombectomy in pulmonary embolism patients, highlighting improved procedural safety.

Key Points

  • Percutaneous mechanical thrombectomy reduces thirty-day bleeding risks and intermediate cardiac complications compared to catheter-directed thrombolysis for pulmonary embolism.
  • Lower odds of intracranial hemorrhage with an odds ratio of 0.46 accompanied mechanical thrombectomy, which also reduced right heart failure hazard to 0.49 across five years.
  • Retrospective cohort study of 2,204 propensity-matched patients highlights enhanced safety, supporting mechanical intervention over catheter-directed thrombolysis in clinical care.

Cite This Study

Tsukagoshi et al. (2024) studied this question.

synapsesocial.com/papers/68e5d588b6db64358756bd23https://doi.org/10.1016/j.jvsv.2024.101958
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months2023 · 28 citations
  2. 2A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism2019 · 569 citations
  3. 3Percutaneous Management of High-Risk Pulmonary Embolism2023 · 65 citations
  4. 4Acute Pulmonary Embolism2022 · 303 citations
  5. 5Mechanical thrombectomy versus catheter directed thrombolysis in patients with pulmonary embolism: A multicenter experience2022 · 34 citations